JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 2008; 107:620-624
© 2008 International Anesthesia Research Society
doi: 10.1213/ane.0b013e3181770b42
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Google Scholar
Right arrow Articles by Schummer, C.
Right arrow Articles by Schummer, W.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schummer, C.
Right arrow Articles by Schummer, W.
Related Collections
Right arrow Critical Care
Right arrow Resuscitation
Right arrow Complications
Right arrow Pharmacology

CRITICAL CARE AND TRAUMA

The Pivotal Role of Vasopressin in Refractory Anaphylactic Shock

Claudia Schummer, MD*, Melanie Wirsing, MD{dagger}, and Wolfram Schummer, MD, DEAA, EDIC{ddagger}

From the *Department for Anesthesiology and Intensive Care Medicine, Friedrich-Schiller-University of Jena, Germany; {dagger}Department of Anesthesiology, Medical Faculty of the University of Heidelberg, Germany; and {ddagger}Department for Anesthesiology and Intensive Care Medicine, Klinikum Quedlinburg, Academic Teaching Hospital of the University Hospital of Magdeburg, Quedlinburg, Germany.

Address correspondence to Wolfram Schummer, MD, DEAA, EDIC, Department for Anesthesiology and Intensive Care Medicine, SRH Zentralklinikum Suhl, Albert-Schweitzer str. 2, 98527 Suhl, Germany. Address e-mail to cwsm.schummer{at}gmx.de.

BACKGROUND: Severe anaphylaxis can be associated with cardiovascular collapse that is difficult to manage and does not respond to treatment with epinephrine. Because anaphylaxis is uncommon, unpredictable and may be fatal, a prospective, randomized, controlled trial in humans on the best management is difficult and guidelines are based on theory and anecdotes only.

METHODS AND RESULTS: We report six cases in which the use of vasopressin was successful in the treatment of anaphylactic shock.

CONCLUSIONS: Standard treatment of anaphylactic shock, including discontinuation of the causative agent, administration of epinephrine, and infusion of IV fluids, did not stabilize cardiocirculatory function, and adding arginine vasopressors resulted in prompt hemodynamic stabilization.




This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
M. W. Dunser, C. Torgersen, and V. Wenzel
Treatment of Anaphylactic Shock: Where Is the Evidence?
Anesth. Analg., August 1, 2008; 107(2): 359 - 361.
[Full Text] [PDF]


Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2008 by the International Anesthesia Research Society.