JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 2008; 107:1041-1044
© 2008 International Anesthesia Research Society
doi: 10.1213/ane.0b013e31817f1e4a
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Yamauchi, M.
Right arrow Articles by Namiki, A.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yamauchi, M.
Right arrow Articles by Namiki, A.
Related Collections
Right arrow Pain Medicine
Right arrow Clinical Pharmacology
Right arrow Pain
Right arrow Pharmacology

ANALGESIA

Continuous Low-Dose Ketamine Improves the Analgesic Effects of Fentanyl Patient-Controlled Analgesia After Cervical Spine Surgery

Masanori Yamauchi, MD, PhD*, Makoto Asano, MD, PhD{dagger}, Masanori Watanabe, MD*, Soushi Iwasaki, MD, PhD*, Shingo Furuse, MD*, and Akiyoshi Namiki, MD, PhD*

From the *Department of Anesthesiology, Sapporo Medical University School of Medicine, Sapporo, Japan; {dagger}Department of Anesthesia, Oji General Hospital, Tomakomai, Japan.

Address correspondence and reprint requests to Masanori Yamauchi, Department of Anesthesiology, Sapporo Medical University School of Medicine, S1 W16 Chuo-ku, Sapporo, Hokkaido 060-8543, Japan. Address e-mail to yamauchi{at}sapmed.ac.jp.

Abstract

BACKGROUND: The effects of fentanyl with ketamine for postoperative pain are unknown. We investigated the adjuvant effects of ketamine for fentanyl patient-controlled analgesia.

METHODS: Cervical and lumbar spine surgery patients were divided into three groups: ketamine 1 mg/kg followed by 42 and 83 µg · kg–1 · h–1 in ketamine-1 and ketamine-2 group, respectively, and a control group. Postoperative patient-controlled analgesia fentanyl was administered with a background infusion.

RESULTS: Pain scores and analgesia requirement in the ketamine-2 group were significantly lower than those of the control group after cervical surgery. Ketamine partially improved the analgesic effects of fentanyl after lumbar surgery.

CONCLUSION: Small-dose ketamine improved the analgesic effects of fentanyl after cervical surgery.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2008 by the International Anesthesia Research Society.